5-Amino-1MQ
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>99% PURITY
HPLC Verified
LAB TESTED
3rd Party Verified
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Description
Product Overview
5-Amino-1MQ is a highly targeted small molecule that acts as a potent, cell-permeable inhibitor of Nicotinamide N-methyltransferase (NNMT). It is extensively utilized in in vitro and in vivo research focusing on cellular metabolism, energy expenditure, and the modulation of fat metabolism.
- Mechanism of Action: By inhibiting NNMT, 5-Amino-1MQ prevents the methylation of nicotinamide, leading to a significant increase in intracellular NAD+ levels.
- Metabolic Research: Promotes increased basal metabolic rate and SIRT1 activation in experimental models, making it a primary candidate for studies on obesity, metabolic syndrome, and cellular aging.
Research Applications
- Investigation of NAD+ salvage pathways and cellular bioenergetics.
- Studies targeting white adipose tissue (WAT) reduction and metabolic reprogramming.
- Aging and cellular senescence research models.
Specifications
- Format: Lyophilized powder / Solid
- Purity: >99% (HPLC verified)
- Storage: Store tightly sealed at -20°C in a dry environment.
RESEARCH USE ONLY. This product is strictly for laboratory research and development purposes. It is NOT for human consumption, diagnostic, therapeutic, or clinical use.
Certificate of Analysis
Third-party testing guarantees >99% purity via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS).
Customer Reviews
Based on 115 authenticated lab entries
Betty T., Lead Researcher
"Quality is acceptable for preliminary trials, though we noticed some minor variations."
Dr. Nancy S.
"Good quality product. Shipping took one day longer than expected, but purity is solid."
Michelle C., Ph.D.
"The COA is accurate and the results in vivo have been remarkably consistent."
Donald E.
"Exactly as described. Will be ordering again for our next trial."
Dr. Elizabeth B.
"Excellent HPLC purity. Consistent results in our murine models."
Michelle N.
"Average results. Meets the minimum purity requirement for our studies."
Linda C.
"Impeccable customer support and clinical-grade quality."
David S.
"Outstanding quality. The mass spec data matches our in-house verification."
Betty K., Ph.D.
"Good quality product. Shipping took one day longer than expected, but purity is solid."
Kimberly T.
"Excellent HPLC purity. Consistent results in our murine models."
Linda E., Principal Investigator
"Outstanding quality. The mass spec data matches our in-house verification."
Michelle S.
"Highest grade peptide we have sourced so far. Highly recommend."
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